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Many potential medical applications for magnetically controlled tetherless devices inside the human body have been proposed, including procedures such as biopsies, blood clot removal, and targeted drug delivery. These devices are capable of wirelessly navigating through fluid-filled cavities in the body, such as the vascular system, eyes, urinary tract, and ventricular system, to reach areas difficult to access via conventional methods. Once at their target location, these devices could perform various medical interventions. This paper focuses on a special type of magnetic tetherless device called a magnetic rotating swimmer, which has internal magnets and propeller fins with a helical shape. To facilitate the design process, an automated geometry generation program using OpenSCAD was developed to create the swimmer design, while computational fluid dynamics simulations using OpenFOAM were employed to calculate the propulsive force produced by the swimmer. Furthermore, an experimental approach is proposed and demonstrated to validate the model. The results show good agreement between simulations and experiments, indicating that the model could be used to develop an automatic geometry optimization pipeline for rotating swimmers. 

Miniature Magnetic Rotating Swimmers (MMRSs) are untethered machines containing magnetic materials. An external rotating magnetic field produces a torque on the swimmers to make them rotate. MMRSs have propeller fins that convert the rotating motion into forward propulsion. This type of robot has been shown to have potential applications in the medical realm. This paper presents new MMRS designs with (1) an increased permanent magnet volume to increase the available torque and prevent the MMRS from becoming stuck inside a thrombus; (2) new helix designs that produce an increased force to compensate for the weight added by the larger permanent magnet volume; (3) different head drill shape designs that have different interactions with thrombi. The two best MMRS designs were tested experimentally by removing a partially dried 1-hour-old thrombus with flow in a bifurcating artery model. The first MMRS disrupted a large portion of the thrombus. The second MMRS retrieved a small remaining piece of the thrombus. In addition, a tool for inserting, retrieving, and switching MMRSs during an experiment is presented and demonstrated. Finally, this paper shows that the two selected MMRS designs can perform accurate 3D path-following. 

Rotating miniature magnetic swimmers are de-vices that could navigate within the bloodstream to access remote locations of the body and perform minimally invasive procedures. The rotational movement could be used, for example, to abrade a pulmonary embolus. Some regions, such as the heart, are challenging to navigate. Cardiac and respiratory motions of the heart combined with a fast and variable blood flow necessitate a highly agile swimmer. This swimmer should minimize contact with the walls of the blood vessels and the cardiac structures to mitigate the risk of complications. This paper presents experimental tests of a millimeter-scale magnetic helical swimmer navigating in a blood-mimicking solution and describes its turning capabilities. The step-out frequency and the position error were measured for different values of turn radius. The paper also introduces rapid movements that increase the swimmer's agility and demonstrates these experimentally on a complex 3D trajectory. 

Heart disease is highly prevalent in developed countries, causing 1 in 4 deaths. In this work we propose a method for a fully automated 4D reconstruction of the left ventricle of the heart. This can provide accurate information regarding the heart wall motion and in particular the hemodynamics of the ventricles. Such metrics are crucial for detecting heart function anomalies that can be an indication of heart disease. Our approach is fast, modular and extensible. In our testing, we found that generating the 4D reconstruction from a set of 250 MRI images takes less than a minute. The amount of time saved as a result of our work could greatly benefit physicians and cardiologist as they diagnose and treat patients. Index Terms—Magnetic Resonance Imaging, segmentation, reconstruction, cardiac, machine learning, ventricle 

Heart disease is highly prevalent in developed countries, causing 1 in 4 deaths. In this work we propose a method for a fully automated 4D reconstruction of the left ventricle of the heart. This can provide accurate information regarding the heart wall motion and in particular the hemodynamics of the ventricles. Such metrics are crucial for detecting heart function anomalies that can be an indication of heart disease. Our approach is fast, modular and extensible. In our testing, we found that generating the 4D reconstruction from a set of 250 MRI images takes less than a minute. The amount of time saved as a result of our work could greatly benefit physicians and cardiologist as they diagnose and treat patients. 

Acquiring volumetric data plays a crucial role in the field of medical imaging. 3D reconstruction is mostly performed using multislice image datasets. The objective of this research is to introduce a magnetic resonance technique for imaging tubular structures and their 3D reconstructions using multiple radially deployed projections. The oblique projection sequence was evaluated on a phantom, and multislice dataset is collected using the same phantom for the reference. To compute the correctness of the 3D reconstruction process, the resulting meshes were compared using the Hausdorff Distance Calculation and Point Cloud Comparison methods. 

The emerging potential of augmented reality (AR) to improve 3D medical image visualization for diagnosis, by immersing the user into 3D morphology is further enhanced with the advent of wireless head-mounted displays (HMD). Such information-immersive capabilities may also enhance planning and visualization of interventional procedures. To this end, we introduce a computational platform to generate an augmented reality holographic scene that fuses pre-operative magnetic resonance imaging (MRI) sets, segmented anatomical structures, and an actuated model of an interventional robot for performing MRI-guided and robot-assisted interventions. The interface enables the operator to manipulate the presented images and rendered structures using voice and gestures, as well as to robot control. The software uses forbidden-region virtual fixtures that alerts the operator of collisions with vital structures. The platform was tested with a HoloLens HMD in silico. To address the limited computational power of the HMD, we deployed the platform on a desktop PC with two-way communication to the HMD. Operation studies demonstrated the functionality and underscored the importance of interface customization to fit a particular operator and/or procedure, as well as the need for on-site studies to assess its merit in the clinical realm. Index Terms—augmented reality, robot-assistance, imageguided interventions.